Pathway to Independence Award (K99/R00)
(Non-Independent and Newly Independent Investigators)
The Pathway to Independence (PI) Award is designed to
facilitate a timely transition from a mentored postdoctoral
research position to a stable independent research position
with independent NIH or other independent research support
at an earlier stage than is currently the norm. The PI award
will provide up to 5 years of support consisting of two phases.
The initial phase will provide 1-2 years of mentored support
for postdoctoral research scientists. This phase will be followed
by up to 3 years of independent support contingent on securing
an independent tenure-track or equivalent research position.
Pathway to Independence Award (K99/R00) Web links:
K99/R00 Program Announcement, PA-07-297:
http://grants.nih.gov/grants/guide/pa-files/PA-07-297.html
Associated
Qs&As: "New Investigators Program/Pathway
to Independence Award, Questions and Answers" (http://grants.nih.gov/grants/new_investigators/QsandAs.htm)
Who is eligible? At the time of application
submission (or resubmission) candidates for this award must
have earned a terminal clinical or research doctorate (including
Ph.D., M.D., D. O., D.C., N.D., D.D.S., D.V.M., Sc.D., D.N.S.,
Pharm. D., or equivalent doctoral degree, or a combined clinical
and research doctoral degree); and have no more than 5 years
(60 months) of research experience since completing the requirements
of the doctoral degree (resubmissions must also comply with
this requirement). The K99/R00 Program Announcement (PA) describes
some exceptions to the 5-year rule; see the PA and associated
"Questions and Answers" document for details. Individuals
whose terminal or research doctorate was awarded more than
60 months before submission of the K99/R00 application are
strongly urged to contact one of the NHLBI Program staff designated
below before submission to determine whether they are eligible
to apply. This confirmation of eligibility should be documented
in a cover letter to accompany the application. Applications
from ineligible individuals will be returned without review.
U.S. citizens and non-U.S. citizens are eligible. There
are additional eligibility criteria detailed in the full K99/R00
Program Announcement; please check carefully before proceeding.
A typical successful candidate will have an impressive record
of research productivity and publications, and will have identified
a unique research direction to pursue after the mentored phase
of the award.
The opportunities? Both mentored research
and independent research support during the early phase of
an investigators' career.
Duration of support? As described above,
up to 5 years of support consisting of two phases. Award of
the independent (R00) phase is not guaranteed.
Where? Domestic for-profit or non-profit
institutions/organizations, or public or private institutions,
such as universities, colleges, hospitals and laboratories,
eligible agencies of the federal government, and NIH intramural
laboratories. All institution/organization types listed above
are eligible for both the mentored and independent phase,
with one exception: ineligible agencies of the Federal government,
such as the NIH intramural program, are eligible only for
the mentored phase. Foreign institutions are not eligible.
Applications due?-
New applications are due February 12, June
12, and October 12.
Resubmitted applications are due March 12, July 12, and November
12.
These are Standard Postmark/Submission Dates (also known
as "send by" dates). Applications are considered
on time if they are sent on or before the appropriate date
listed and a proof of mailing is provided.
Budget:
Mentored phase (K99): Salary:
up to $75,000 plus fringe benefits per year. Research Support:
up to $25,00 per year. F&A costs will be provided at 8%
of modified direct costs (to extramural sponsoring institutions
only).
Independent investigator phase (R00): Total
cost may not exceed $249,000 per year. This amount includes
salary, fringe benefits, research support allowance and applicable
F&A costs. F&A costs will be reimbursed at the extramural
sponsoring institution’s F&A rate. Facilities and
administrative costs requested by consortium participants
are included in the total cost limitation.
How to apply: For the October and November
2008 application receipt dates, use
the application form PHS 398, at: http://grants.nih.gov/grants/funding/phs398/phs398.html.
[The K99/R00 mechanism has not yet converted to electronic
submissions. Conversion to electronic submission is
planned for the February 12, 2009 and later receipt dates.
Further
details regarding the transition process are at http://era.nih.gov/ElectronicReceipt.]
Applications must be prepared using the relevant Career Development
Award (CDA) application package, as specified in PA-07-297.
The content, format, and page limitations for a CDA application
are substantially different from those in an R01 research-project
application. Note in particular that the "Candidate"
and "Research Plan" (sections A-D) combined may
not exceed 25 pages. There are special instructions for preparing
individual career award applications in the PHS 398, in Part
1, Section 7. Do not use the instructions for regular research
grants found in the PHS 398.
Submit a signed, typewritten original of the application,
including the checklist, and five signed
photocopies in one package to:
Center for Scientific Review
National Institutes of Health -----------------------------------------------------------------------------------
- - - - - -
6701 Rockledge Drive, Room 1040, MSC 7710
Bethesda, MD 20892-7710 (U.S. Postal Service Express or
regular mail)
Bethesda, MD 20817 (for express/courier service; non-USPS
service)
Application packages should include a cover letter indicating
preferred institute assignment for review and possible funding,
and if applicable, information on prior confirmation of eligibility
for the K99/R00 award.
Note that new and resubmitted applications must include at
least three sealed letters of reference attached to the face
page of the original application. Applications submitted without
the required number of reference letters will be considered
incomplete and will be returned without review.
The NHLBI has developed an additional
document, Fact Sheet: K99s Transitioning
to R00 (http://www.nhlbi.nih.gov/funding/training/redbook/newk99r00fact.htm)
which provides application instructions for NHLBI K99 awardees
transitioning from the mentored phase of the K99 to the independent
research phase of the R00.
The NHLBI Website also lists training
programs under the category Requests
for Applications/Proposals & Program Announcements
with the application receipt date.
Please contact the following NHLBI staff member if you have
questions about this award:
Direct your questions about NHLBI intramural programmatic
issues to:
Herbert Geller, Ph.D.
Director, Office of Education
Division of Intramural Research
National Heart, Lung, and Blood Institute
Building 10, Room 2N242
10 Center Drive, MSC 1754
Bethesda , MD 20892-1754
Phone: (301) 451-9440
FAX: (301) 594-8133
Email: direducation@nhlbi.nih.gov
Direct your questions about NHLBI extramural programmatic
issues to:
Helena O. Mishoe, Ph.D., MPH
Office of Research Training and Minority Health
National Heart, Lung, and Blood Institute
6701 Rockledge Drive , Room 9180, MSC 7913
Bethesda , MD 20892-7913
Phone: 301-451-5081
FAX: (301) 480-0862
Email: mishoeh@nhlbi.nih.gov
October 2008 |